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Welcome to the Esther web-service.

Esther is an interface to a suite of tools for discrete simulation a reverse-engineering of gene regulatory and signal transduction networks. For modelling we employ the framework of asynchronous boolean or multi-valued (commonly referred to as Thomas or Qualitative) networks. Currently Esther allows for conduction of the following tasks:

For a more thorough description of the platform please refer to the Guide page. The theoretical background of the computation is described in this pdf.

To access the tool-set and also obtain a server-side storage and computational capacity, please register. An e-mail with an activation link for your account will be sent to you within 24 hours.

News:

Esther is being developed in collaboration of members of the Systems Biology Laboratory of Masaryk University and the Discrete Biomathematics group of Freie Universit├Ąt of Berlin.

The source code is distributed under GNU general public license v3 and is available on GitHub.