Esther Home


Welcome to the Esther web-service.

Esther is an interface to a suite of tools for discrete simulation a reverse-engineering of gene regulatory and signal transduction networks. For modelling we employ the framework of asynchronous boolean or multi-valued (commonly referred to as Thomas or Qualitative) networks. Currently Esther allows for conduction of the following tasks:

For a more thorough description of the platform please refer to the Guide page. The theoretical background of the computation is described in this pdf.

To access the tool-set and also obtain a server-side storage and computational capacity, please register. An e-mail with an activation link for your account will be sent to you within 24 hours.


Esther is being developed in collaboration of members of the Systems Biology Laboratory of Masaryk University and the Discrete Biomathematics group of Freie Universit├Ąt of Berlin.

The source code is distributed under GNU general public license v3 and is available on GitHub.